Reduced medial prefrontal cortex (mPFC) neuronal activity is usually associated with
Reduced medial prefrontal cortex (mPFC) neuronal activity is usually associated with interpersonal defeat-induced depression- and anxiety-like behaviors in mice. optogenetic activation of mPFC neurons in vulnerable mice reverses many behavioral abnormalities noticed after chronic interpersonal defeat stress. As a result, we hypothesized that optogenetic arousal of cortical projections would recovery the pathological ramifications of CCK … [Read more…]