Gonadotropin-releasing hormone (GnRH) receptors are expressed in prostate cancer, specifically in
Gonadotropin-releasing hormone (GnRH) receptors are expressed in prostate cancer, specifically in the most aggressive stage of the tumor (castration-resistant prostate cancer, CRPC) for which the standard treatment, docetaxel-based chemotherapy, can only improve the median survival time by few months. of GnRH agonists, experiments were performed in p53-null PC3 cells. We found that GnRH agonists fail … [Read more…]