Background Familial hyperaldosteronism type We (FH-I) is due to the unequal
Background Familial hyperaldosteronism type We (FH-I) is due to the unequal recombination between your 11beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) genes, leading to the generation of the CYP11B1/B2 chimeric gene and unusual adrenal aldosterone production. model, both enzymes demonstrated similar obvious kinetic variables (Kilometres?=?1.191 microM and Vmax?=?27.08 microM/24?h for ASCE and Kilometres?=?1.163 microM and Vmax?=?36.98 … [Read more…]