Japanese encephalitis virus (JEV), a mosquito-borne flavivirus that triggers severe individual
Japanese encephalitis virus (JEV), a mosquito-borne flavivirus that triggers severe individual disease, has been proven to block the interferon (IFN)-induced Janus kinase sign transducer and activation of transcription (Jak-Stat) signaling cascade by preventing Tyk2 tyrosine phosphorylation and Stat activation. can be an IFN antagonist which it may are likely involved in blocking IFN-stimulated Jak-Stat signaling … [Read more…]