Wnt proteins are secreted glycoproteins that bind towards the N-terminal extra-cellular
Wnt proteins are secreted glycoproteins that bind towards the N-terminal extra-cellular cysteine-rich domain from the Frizzled (Fzd) receptor family. canonical Wnt signaling pathway. Furthermore, pharmacological inhibition of Fzd7 by little interfering peptides or a little molecule inhibitor suppressed -catenin-dependent tumor cell development. Consequently, targeted inhibition of Fzd7 represents a logical and promising fresh approach for … [Read more…]