? OxLDL promotes induction of pATM and p21 in fibroblasts/endothelial cells.
? OxLDL promotes induction of pATM and p21 in fibroblasts/endothelial cells. A-T, than regular fibroblasts. Last, pre-treatment of cells with ammonium pyrrolidine dithiocarbamate, a powerful antioxidant and inhibitor of transcription aspect nuclear aspect B, decreases oxLDL-induced reactive air species development. Our data signifies that ATM features in the defence against oxLDL-mediated cytotoxicity. 1.?Launch Reactive oxygen … [Read more…]