TatCN21 is a membrane permeable CaMKII inhibitor produced from the inhibitor
TatCN21 is a membrane permeable CaMKII inhibitor produced from the inhibitor proteins CaMKIIN. CaMKII-polyribosome aggregates created regularly with 20 M tatCN21, but minimally or never with 5 M. Nevertheless, these aggregates aren’t induced by another CaMKII inhibitor, KN93. Development of CaMKII-polyribosome aggregates was totally reversible within 1 h after washout of tatCN21. Ramifications of tatCN21 … [Read more…]