(damage-regulated autophagy modulator), an integral regulator of autophagy, resulting in autophagic
(damage-regulated autophagy modulator), an integral regulator of autophagy, resulting in autophagic induction. may get a misfolded and partly denatured conformation5 conferring towards the protein high tendency to create micro- and macro-aggregates.3 The effect is accumulation of hyperstable mutp53 protein in tumors. The principal aftereffect of these mutations may be the impairment of p53 to activate … [Read more…]