Somatic mutations in spliceosome genes are detectable in 50% of patients
Somatic mutations in spliceosome genes are detectable in 50% of patients with myelodysplastic syndromes (MDS). United Claims1,2. MDS are a heterogeneous group of clonal haematopoietic come cell disorders characterized by peripheral blood cytopaenias and progenitor growth; approximately one-third of individuals will transform to a secondary acute myeloid leukaemia (AML) that offers a poor diagnosis3. The … [Read more…]