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Targeting the ubiquitin–proteasome system for cancer therapy

ARRY-334543

Many lead molecules determined in drug discovery campaigns are eliminated from

January 31, 2018 by Katherine Lewis Leave a Comment

Many lead molecules determined in drug discovery campaigns are eliminated from consideration due to poor solubility and low cell permeability. cancer cells in vitro and tumors in vivo without toxic adjuvants. These results suggest SVS-1 can serve as a simple, effective delivery platform for molecules with poor solubility and permeability. design of an anticancer peptide, … [Read more…]

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