Background Ras connected with diabetes (Rad) inhibits vascular lesion formation by
Background Ras connected with diabetes (Rad) inhibits vascular lesion formation by lowering the attachment and migration of vascular clean muscle cells (VSMCs). 2 (NAB2) repressed PDGF-induced Rad up-regulation inside a dose-dependent manner. Direct binding of Egr-1 to the Rad promoter region was further confirmed by chromatin immunoprecipitation assays. Conclusions Our results demonstrate that Rad is … [Read more…]