Fasiglifam – Targeting the ubiquitin–proteasome system for cancer therapy

Background Contrast-induced nephropathy (CIN) may be the primary complication of contrast

December 2, 2018 by Katherine Lewis Leave a Comment

Background Contrast-induced nephropathy (CIN) may be the primary complication of contrast media administration (CM) in sufferers undergoing coronary angiography (CAG) and percutaneous coronary intervention (PCI). 1.03-2.18, P =0.03). The magnitude of association was considerably strengthened in the observational research (OR=1.84, 95%CI 1.19-2.85, P=0.006) however, not in the randomized Fasiglifam controlled studies (OR=0.88, 95%CI 0.41-1.90 P=0.74). … [Read more…]

The epithelial-mesenchymal transition (EMT) has been postulated as a mechanism by

February 12, 2018 by Katherine Lewis Leave a Comment

The epithelial-mesenchymal transition (EMT) has been postulated as a mechanism by which cancer cells acquire the invasive and stem-like traits necessary for distant metastasis. expression of vimentin and EpCAM. mice (but not mice with deletion only) exhibited growth of cells with EMT (EpCAM+/Vim-GFP+) and mesenchymal (EpCAM?/Vim-GFP+) characteristics at the main tumor site and in blood … [Read more…]