To identify genes influencing blood pressure response to an angiotensin II
To identify genes influencing blood pressure response to an angiotensin II receptor blocker, single nucleotide polymorphisms recognized by genome-wide association analysis of the response to candesartan were validated by reverse direction associations with the response to a thiazide diuretic, hydrochlorothiazide. AA genotype, the mean systolic BP/diastolic BP reactions to hydrochlorothiazide were 4.7/6.3 mmHg less for … [Read more…]