Tumor genomes frequently contain somatic copy number alterations (SCNA) that can
Tumor genomes frequently contain somatic copy number alterations (SCNA) that can significantly perturb the manifestation level of affected genes and thus disrupt pathways controlling normal growth. candidate genes potentially involved in tumorigenesis. Since few of these alterations were recurrent across our samples we used a protein network-guided approach to determine whether any pathways were TLK2 … [Read more…]