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Targeting the ubiquitin–proteasome system for cancer therapy

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Background and Purpose Age-related changes in the cerebrovasculature, including blood-brain barrier

February 9, 2018 by Katherine Lewis Leave a Comment

Background and Purpose Age-related changes in the cerebrovasculature, including blood-brain barrier (BBB) disruption, are emerging as potential risks for diverse neurological conditions. proteins in the cortical microvessels were reduced in BubR1H/H mice, consistent with a compromised BBB honesty from permeability assays. Importantly, the protection of microvessels by end-feet of aquaporin 4 (AQP4)-immunoreactive astrocytes was not … [Read more…]

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