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Targeting the ubiquitin–proteasome system for cancer therapy

MK-4305

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid

February 15, 2018 by Katherine Lewis Leave a Comment

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells with the capacity to inhibit immunological responses. their immunosuppressive function and acquired instead an antigen-presenting phenotype with the ability to induce MK-4305 specific T-cell expansion. Importantly, we found that MDSC co-injected h.c. with CT26 tumor cells lost their ability to support tumor growth … [Read more…]

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