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Targeting the ubiquitin–proteasome system for cancer therapy

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Considerable energy and resources have been invested in increasing mass spectrometry

September 7, 2017 by Katherine Lewis Leave a Comment

Considerable energy and resources have been invested in increasing mass spectrometry (MS) instrumentation, up-stream sample preparation protocols, and database search strategies to maximize peptide and protein identifications. results were found to be resin-specific and not generalizable. Our investigation demonstrates the often unappreciated importance of optimizing sample loading conditions to reflect the seeks of the research … [Read more…]

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