The initiating somatic genetic events in chordoma development have not yet
The initiating somatic genetic events in chordoma development have not yet been identified. could be discerned. However, the and loci in 9p21 were homo- or heterozygously lost in 70% of the tumours, a finding corroborated by fluorescence hybridisation, suggesting that inactivation of these genes constitute an important step in chordoma development. hybridisation (FISH), include loss … [Read more…]