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Targeting the ubiquitin–proteasome system for cancer therapy

PLX4032

Rather than targeting tumour cells directly, elements of the tumour microenvironment

February 9, 2018 by Katherine Lewis Leave a Comment

Rather than targeting tumour cells directly, elements of the tumour microenvironment can be modulated to sensitize tumours to the effects of therapy. important for EC expansion under hypoxia and hypoxia-related angiogenesis1. Similarly, the ataxia telangiectasia-mutated kinase, a expert regulator of the DDR runs pathological angiogenesis2. Given the essential part of hypoxia, oxidative stress and DNA … [Read more…]

Posted in: Blogging Tagged: PLX4032, Rabbit Polyclonal to MRPL47

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