History PG11047 is a book conformationally restricted analog from the normal
History PG11047 is a book conformationally restricted analog from the normal polyamine spermine that lowers cellular endogenous polyamine amounts and competitively inhibits normal polyamine functions leading to cancer cell growth inhibition. for 6 weeks. Results PG11047 shown a concentration-response pattern consistent with cytostatic activity. The median relative IC50 for PG11047 was 71 nM. Cell lines … [Read more…]