Supplementary Materialsoncotarget-11-801-s001
Supplementary Materialsoncotarget-11-801-s001. tracing of deuterated serine uncovered that SLC25A32 knock-down will not affect the mitochondrial/cytosolic folate flux as assessed by Liquid Chromatography combined Mass Spectrometry (LC-MS). Rather, SLC25A32 inhibition leads to a respiratory string dysfunction on the FAD-dependent complicated II enzyme, induction of Reactive Air Types (ROS) and depletion of decreased glutathione (GSH), which impairs … [Read more…]