Level of resistance to platinum-based chemotherapy may be the main hurdle
Level of resistance to platinum-based chemotherapy may be the main hurdle to treating epithelial ovarian tumor. the Wnt/-catenin particular inhibitor iCG-001 potently sensitized cells to cisplatin and reduced stem-cell regularity in platinum resistant cells. Used jointly, our data may be the first record providing evidence the fact that Wnt/-catenin signaling pathway maintains stem-like properties and … [Read more…]